Patient reported outcomes from patients treating depression. Sample Size 6903

Learn More:

Anderson, D.M., Rees, D.I., and Sabia, J.J. (2012, January 7). High on Life? Medical Marijuana Laws and Suicide. Cato Institute, 17. Retrieved from

Ashton, C.H., and Moore, P.B. (2011, October). Endocannabinoid system dysfunction in mood and related disorders. Acta Psychiatrica Scandinavica, 124(4), 250-61. Retrieved from

Bricker, J.B., Russo, J., Stein, M.B., Sherbourne, C., Craske, M., Schraufnagel, T.J., and Roy-Byrne, P. (2007). Does occasional cannabis use impact anxiety and depression treatment outcomes?: Results from a randomized effectiveness trial. Depression and Anxiety, 24(6), 392-8. Retrieved from

Denson, T.F., and Earleywine, M. (2006, April). Decreased depression in marijuana users. Addictive Behaviors, 31(4), 738-742. Retrieved from

Depression (major depressive disorder). (2015, July 22). Mayo Clinic. Retrieved from

Gorzalka, B.B., and Hill, M.N. (2011, August 15). Putative role of endocannabinoid signaling in the etiology of depression and actions of antidepressants. Progress in Neuro-Pschopharmacology & Biological Psychiatry, 35(7), 1575-85. Retrieved from

Haj-Dahmane, S., and Shen, R.Y. (2014, October 29). Chronic stress impaires α1-adrenoceptor-induced endocannabinoid-dependent synaptic plasticity in the dorsal raphe nucleus. The Journal of Neuroscience, 34(44), 14560-14570. Retrieved from

Hill, M.N., and Gorzalka, B.B. (2009, December). The endocannabinoid system and the treatment of mood and anxiety disorders. CNS & Neurological Disorders Drug Targets, 8(6), 451-8. Retrieved from

Hill, M.N., Hillard, C.J., Bambico, F.R., Patel., S, Gorzalka, B.B., and Gobbi, G. (2009, September). The therapeutic potential of the endocannabinoid system for the development of a novel class of antidepressants. Trends in Pharmacological Sciences, 30(9), 484-93. Retrieved from

Hill, M. N., Miller, G. E., Carrier, E. J., Gorzalka, B. B., & Hillard, C. J. (2009). Circulating Endocannabinoids and N-Acyl Ethanolamines Are Differentially Regulated in Major Depression and Following Exposure to Social Stress. Psychoneuroendocrinology34(8), 1257–1262. Retrieved from

Ho, W. V., Hill, M. N., Miller, G. E., Gorzalka, B. B., & Hillard, C. J. (2012). Serum contents of endocannabinoids are correlated with blood pressure in depressed women. Lipids in Health and Disease11, 32. Retrieved from

Jiang, W., Zhang, Y., Xiao, L., Van Cleemput, J., Ji, S.P., Bai, G., and Zhang, X. (2005, November). Cannabinoids promote embryonic and adult hippocampus neurogenesis and produce anxiolytic- and antidepressant-like effects. Journal of Clinical Investigation, 115(11), 3104-3116. Retrieved from

Smaga, I., Bystrowska, B., Gawliński, D., Pomierny, B., Stankowicz, P., & Filip, M. (2014). Antidepressants and Changes in Concentration of Endocannabinoids and N-Acylethanolamines in Rat Brain Structures. Neurotoxicity Research26(2), 190–206. Retrieved from

What Is Depression? (n.d.). National Institute of Mental Health. Retrieved from

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